If you are about to deploy Skype for Business Mac, you will first need to remove Lync 2011 and Skype for Business Mac Beta.
Starting today, Skype for Business Mac users will be able to see meetings in the Skype business client through built-in Outlook calendar integration, joining them with a click. The Skype for Business Mac Client will be released to accepted customers the first week of March All future emails will come from the Product Group to the customer.
This is a script to remove all items listed on How to perform a clean uninstall of Lync for Mac 2011. In addition, it will remove the corresponding Skype for Business Mac Beta files. The script removes Apps, caches, cookies, Keychain entries, preferences, receipts and logs. (But not Dock items). There is a similar, more mature script with feedback posted on jamf Nation here, though it's not as thorough.
Skype For Business Mac Client Beta Download
I've tested this script in my AD environment.
Skype For The Mac
Feel free to improve upon this.